Alpha, beta Synuclein (AA 119-140) anticorps

N° du produit ABIN306414

Cet anticorps anti- est un anticorps Souris Monoclonal détectant dans WB, ELISA, ICC, IF et FACS. Adapté pour Humain.

Aperçu rapide pour Alpha, beta Synuclein (AA 119-140) anticorps (ABIN306414)

Antigène: Alpha, beta Synuclein

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 3B6

Détail du produit

Épitope: AA 119-140

Purification: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogène: Recombinant human a-synuclein (119-140aa) purified from E. coli

Isotype: IgG1 kappa

Information d'application

Indications d'application: Recommended dilution 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Alpha, beta Synuclein

Autre désignation: Synuclein-alpha/beta

Sujet: Alpha-synuclein (amino acids 119-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-Abeta component of amyloid plaques is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer's disease brain.

NCBI Accession: NP_000336, NP_003076